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DNA binding proteins explore multiple local configurations during docking via rapid rebinding

Finding the target site and associating in a specific orientation are essential tasks for DNA-binding proteins. In order to make the target search process as efficient as possible, proteins should not only rapidly diffuse to the target site but also dynamically explore multiple local configurations...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ganji, Mahipal, Docter, Margreet, Le Grice, Stuart F.J., Abbondanzieri, Elio A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041478/
https://ncbi.nlm.nih.gov/pubmed/27471033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw666
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