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Combination probes with intercalating anchors and proximal fluorophores for DNA and RNA detection

A new class of modified oligonucleotides (combination probes) has been designed and synthesised for use in genetic analysis and RNA detection. Their chemical structure combines an intercalating anchor with a reporter fluorophore on the same thymine nucleobase. The intercalator (thiazole orange or be...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Qiu, Jieqiong, Wilson, Adam, El-Sagheer, Afaf H., Brown, Tom
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041472/
https://ncbi.nlm.nih.gov/pubmed/27369379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw579
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