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PTBP1 modulation of MCL1 expression regulates cellular apoptosis induced by antitubulin chemotherapeutics
Myeloid cell leukemia sequence 1 (MCL1), an anti-apoptotic BCL2 family protein, is a key regulator of intrinsic apoptosis. Normal cells require strict control over MCL1 expression with aberrant MCL1 expression linked to the emergence of various diseases and chemoresistance. Previous studies have det...
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| Publicado no: | Cell Death Differ |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5041196/ https://ncbi.nlm.nih.gov/pubmed/27367564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.60 |
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