The activity of the glucocorticoid receptor is regulated by SUMO conjugation to FKBP51

FK506-binding protein 51 (FKBP51) regulates the activity of the glucocorticoid receptor (GR), and is therefore a key mediator of the biological actions of glucocorticoids. However, the understanding of the molecular mechanisms that govern its activity remains limited. Here, we uncover a novel regula...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Antunica-Noguerol, M, Budziñski, M L, Druker, J, Gassen, N C, Sokn, M C, Senin, S, Aprile-Garcia, F, Holsboer, F, Rein, T, Liberman, A C, Arzt, E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041187/
https://ncbi.nlm.nih.gov/pubmed/27177020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.44
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