RSUME Enhances Glucocorticoid Receptor SUMOylation and Transcriptional Activity

Glucocorticoid receptor (GR) activity is modulated by posttranslational modifications, including phosphorylation, ubiquitination, and SUMOylation. The GR has three SUMOylation sites: lysine 297 (K297) and K313 in the N-terminal domain (NTD) and K721 within the ligand-binding domain. SUMOylation of t...

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Detalhes bibliográficos
Main Authors: Druker, Jimena, Liberman, Ana C., Antunica-Noguerol, María, Gerez, Juan, Paez-Pereda, Marcelo, Rein, Theo, Iñiguez-Lluhí, Jorge A., Holsboer, Florian, Arzt, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648064/
https://ncbi.nlm.nih.gov/pubmed/23508108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01470-12
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