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Cigarette smoke reversibly activates hypoxia-inducible factor 1 in a reactive oxygen species-dependent manner

Cigarette smoke (CS) is a major contributor to the development of a large number of fatal and debilitating disorders. However, the precise molecular mechanisms underlying the effects of CS in lung disease are largely unknown. To elucidate these pathophysiological processes, we examined the in vitro...

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Publicat a:Sci Rep
Autors principals: Daijo, Hiroki, Hoshino, Yuma, Kai, Shinichi, Suzuki, Kengo, Nishi, Kenichiro, Matsuo, Yoshiyuki, Harada, Hiroshi, Hirota, Kiichi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041075/
https://ncbi.nlm.nih.gov/pubmed/27680676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34424
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