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Cigarette smoke reversibly activates hypoxia-inducible factor 1 in a reactive oxygen species-dependent manner

Cigarette smoke (CS) is a major contributor to the development of a large number of fatal and debilitating disorders. However, the precise molecular mechanisms underlying the effects of CS in lung disease are largely unknown. To elucidate these pathophysiological processes, we examined the in vitro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Daijo, Hiroki, Hoshino, Yuma, Kai, Shinichi, Suzuki, Kengo, Nishi, Kenichiro, Matsuo, Yoshiyuki, Harada, Hiroshi, Hirota, Kiichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041075/
https://ncbi.nlm.nih.gov/pubmed/27680676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34424
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