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Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists
The interferon (IFN) induced anti-viral response is amongst the earliest and most potent of the innate responses to fight viral infection. The induction of the Janus kinase/signal transducer and activation of transcription (JAK/STAT) signalling pathway by IFNs leads to the upregulation of hundreds o...
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| 發表在: | Vaccines (Basel) |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5041017/ https://ncbi.nlm.nih.gov/pubmed/27367734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines4030023 |
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