HA Antibody-Mediated FcγRIIIa Activity Is Both Dependent on FcR Engagement and Interactions between HA and Sialic Acids

Interactions with receptors for the Fc region of IgG (FcγRs) have been shown to contribute to the in vivo protection against influenza A viruses provided by broadly neutralizing antibodies (bnAbs) that bind to the viral hemagglutinin (HA) stem. In particular, Fc-mediated antibody-dependent cellular...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Cox, Freek, Kwaks, Ted, Brandenburg, Boerries, Koldijk, Martin H., Klaren, Vincent, Smal, Bastiaan, Korse, Hans J. W. M., Geelen, Eric, Tettero, Lisanne, Zuijdgeest, David, Stoop, Esther J. M., Saeland, Eirikur, Vogels, Ronald, Friesen, Robert H. E., Koudstaal, Wouter, Goudsmit, Jaap
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2016
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040702/
https://ncbi.nlm.nih.gov/pubmed/27746785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00399
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