HA Antibody-Mediated FcγRIIIa Activity Is Both Dependent on FcR Engagement and Interactions between HA and Sialic Acids

Interactions with receptors for the Fc region of IgG (FcγRs) have been shown to contribute to the in vivo protection against influenza A viruses provided by broadly neutralizing antibodies (bnAbs) that bind to the viral hemagglutinin (HA) stem. In particular, Fc-mediated antibody-dependent cellular...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Cox, Freek, Kwaks, Ted, Brandenburg, Boerries, Koldijk, Martin H., Klaren, Vincent, Smal, Bastiaan, Korse, Hans J. W. M., Geelen, Eric, Tettero, Lisanne, Zuijdgeest, David, Stoop, Esther J. M., Saeland, Eirikur, Vogels, Ronald, Friesen, Robert H. E., Koudstaal, Wouter, Goudsmit, Jaap
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040702/
https://ncbi.nlm.nih.gov/pubmed/27746785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00399
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