Targeting ABCB1-mediated tumor multidrug resistance by CRISPR/Cas9-based genome editing

The RNA-guided clustered regularly interspaced short palindromic (CRISPR) in combination with a CRISPR-associated nuclease 9 (Cas9) nuclease system is a new rapid and precise technology for genome editing. In the present study, we applied the CRISPR/Cas9 system to target ABCB1 (also named MDR1) gene...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Yang, Yang, Qiu, Jian-Ge, Li, Yong, Di, Jin-Ming, Zhang, Wen-Ji, Jiang, Qi-Wei, Zheng, Di-Wei, Chen, Yao, Wei, Meng-Ning, Huang, Jia-Rong, Wang, Kun, Shi, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040697/
https://ncbi.nlm.nih.gov/pubmed/27725879
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