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Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta

Imprinted genes are expressed primarily from one parental allele by virtue of a germ line epigenetic process. Achaete-scute complex homolog 2 (Ascl2 aka Mash2) is a maternally expressed imprinted gene that plays a key role in placental and intestinal development. Loss-of-function of Ascl2 results in...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Tunster, S.J., McNamara, G.I., Creeth, H.D.J., John, R.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040514/
https://ncbi.nlm.nih.gov/pubmed/27542691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.08.014
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