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Stem cell function and stress response are controlled by protein synthesis

Whether protein synthesis and cellular stress response pathways interact to control stem cell function is currently unknown. Here, we show that skin stem cells synthesize less protein than their immediate progenitors in vivo, even when forced to proliferate. Our analyses reveal that activation of st...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Blanco, Sandra, Bandiera, Roberto, Popis, Martyna, Hussain, Shobbir, Lombard, Patrick, Aleksic, Jelena, Sajini, Abdulrahim, Tanna, Hinal, Cortés-Garrido, Rosana, Gkatza, Nikoletta, Dietmann, Sabine, Frye, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040503/
https://ncbi.nlm.nih.gov/pubmed/27306184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18282
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