NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs

Autosomal-recessive loss of the NSUN2 gene has been identified as a causative link to intellectual disability disorders in humans. NSun2 is an RNA methyltransferase modifying cytosine-5 in transfer RNAs (tRNAs), yet the identification of cytosine methylation in other RNA species has been hampered by...

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Detalhes bibliográficos
Main Authors: Hussain, Shobbir, Sajini, Abdulrahim A., Blanco, Sandra, Dietmann, Sabine, Lombard, Patrick, Sugimoto, Yoichiro, Paramor, Maike, Gleeson, Joseph G., Odom, Duncan T., Ule, Jernej, Frye, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730056/
https://ncbi.nlm.nih.gov/pubmed/23871666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.06.029
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