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High-Resolution Identification of Specificity Determining Positions in the LacI Protein Family Using Ensembles of Sub-Sampled Alignments

Since the advent of large-scale genomic sequencing, and the consequent availability of large numbers of homologous protein sequences, there has been burgeoning development of methods for extracting functional information from multiple sequence alignments (MSAs). One type of analysis seeks to identif...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sloutsky, Roman, Naegle, Kristen M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040260/
https://ncbi.nlm.nih.gov/pubmed/27681038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162579
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