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Airway Factor XIII associates with type-2 inflammation and airway obstruction in asthma

BACKGROUND: Coagulation factor XIII (FXIII) plays an important role in wound healing by stabilizing fibrin clots and crosslinking extracellular matrix proteins. FXIII is expressed in cells of the monocyte/macrophage and dendritic cell lineages in response to type-2 cytokines. OBJECTIVE: We sought to...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Esnault, Stephane, Kelly, Elizabeth A., Sorkness, Ronald L., Evans, Michael D., Busse, William W., Jarjour, Nizar N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040212/
https://ncbi.nlm.nih.gov/pubmed/26525229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.05.053
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