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Time-resolved dual RNA-seq reveals extensive rewiring of lung epithelial and pneumococcal transcriptomes during early infection

BACKGROUND: Streptococcus pneumoniae, the pneumococcus, is the main etiological agent of pneumonia. Pneumococcal infection is initiated by bacterial adherence to lung epithelial cells. The exact transcriptional changes occurring in both host and microbe during infection are unknown. Here, we develop...

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Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Aprianto, Rieza, Slager, Jelle, Holsappel, Siger, Veening, Jan-Willem
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039909/
https://ncbi.nlm.nih.gov/pubmed/27678244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1054-5
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