Extracellular ATP is involved in dsRNA-induced MUC5AC production via P2Y2R in human airway epithelium

BACKGROUND: In response to tissue damage or inflammation, adenosine-5′-triphosphate (ATP) is released into the extracellular compartment and has been demonstrated to augment inflammation via purinergic P2 receptors (P2Rs). Recently, ATP has been shown to be increased in the airways of COPD patients....

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Bibliografische gegevens
Gepubliceerd in:Respir Res
Hoofdauteurs: Shishikura, Yutaka, Koarai, Akira, Aizawa, Hiroyuki, Yamaya, Mutsuo, Sugiura, Hisatoshi, Watanabe, Mika, Hashimoto, Yuichiro, Numakura, Tadahisa, Makiguti, Tomonori, Abe, Kyoko, Yamada, Mituhiro, Kikuchi, Toshiaki, Hoshikawa, Yasushi, Okada, Yoshinori, Ichinose, Masakazu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039824/
https://ncbi.nlm.nih.gov/pubmed/27677339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0438-0
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