Extracellular ATP is involved in dsRNA-induced MUC5AC production via P2Y2R in human airway epithelium

BACKGROUND: In response to tissue damage or inflammation, adenosine-5′-triphosphate (ATP) is released into the extracellular compartment and has been demonstrated to augment inflammation via purinergic P2 receptors (P2Rs). Recently, ATP has been shown to be increased in the airways of COPD patients....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Respir Res
Egile Nagusiak: Shishikura, Yutaka, Koarai, Akira, Aizawa, Hiroyuki, Yamaya, Mutsuo, Sugiura, Hisatoshi, Watanabe, Mika, Hashimoto, Yuichiro, Numakura, Tadahisa, Makiguti, Tomonori, Abe, Kyoko, Yamada, Mituhiro, Kikuchi, Toshiaki, Hoshikawa, Yasushi, Okada, Yoshinori, Ichinose, Masakazu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039824/
https://ncbi.nlm.nih.gov/pubmed/27677339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0438-0
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