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A new design for a green calcium indicator with a smaller size and a reduced number of calcium-binding sites

Genetically encoded calcium indicators (GECIs) are mainly represented by two- or one-fluorophore-based sensors. One type of two-fluorophore-based sensor, carrying Opsanus troponin C (TnC) as the Ca(2+)-binding moiety, has two binding sites for calcium ions, providing a linear response to calcium ion...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Barykina, Natalia V., Subach, Oksana M., Doronin, Danila A., Sotskov, Vladimir P., Roshchina, Marina A., Kunitsyna, Tatiana A., Malyshev, Aleksey Y., Smirnov, Ivan V., Azieva, Asya M., Sokolov, Ilya S., Piatkevich, Kiryl D., Burtsev, Mikhail S., Varizhuk, Anna M., Pozmogova, Galina E., Anokhin, Konstantin V., Subach, Fedor V., Enikolopov, Grigori N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039633/
https://ncbi.nlm.nih.gov/pubmed/27677952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34447
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