NTnC-like genetically encoded calcium indicator with a positive and enhanced response and fast kinetics

The NTnC genetically encoded calcium indicator has an advantageous design because of its smaller size, GFP-like N- and C-terminal ends and two-fold reduced number of calcium binding sites compared with widely used indicators from the GCaMP family. However, NTnC has an inverted and modest calcium res...

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Publicado no:Sci Rep
Main Authors: Barykina, Natalia V., Doronin, Danila A., Subach, Oksana M., Sotskov, Vladimir P., Plusnin, Viktor V., Ivleva, Olga A., Gruzdeva, Anna M., Kunitsyna, Tatiana A., Ivashkina, Olga I., Lazutkin, Alexander A., Malyshev, Aleksey Y., Smirnov, Ivan V., Varizhuk, Anna M., Pozmogova, Galina E., Piatkevich, Kiryl D., Anokhin, Konstantin V., Enikolopov, Grigori, Subach, Fedor V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189086/
https://ncbi.nlm.nih.gov/pubmed/30323302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33613-6
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