Depolymerization of Fucosylated Chondroitin Sulfate with a Modified Fenton-System and Anticoagulant Activity of the Resulting Fragments

Fucosylated chondroitin sulfate (fCS) from sea cucumber Isostichopus badionotus (fCS-Ib) with a chondroitin sulfate type E (CSE) backbone and 2,4-O-sulfo fucose branches has shown excellent anticoagulant activity although has also show severe adverse effects. Depolymerization represents an effective...

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Vydáno v:Mar Drugs
Hlavní autoři: Li, Jun-hui, Li, Shan, Zhi, Zi-jian, Yan, Lu-feng, Ye, Xing-qian, Ding, Tian, Yan, Lei, Linhardt, Robert John, Chen, Shi-guo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039541/
https://ncbi.nlm.nih.gov/pubmed/27657094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14090170
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