Differential Activation of TRP Channels in the Adult Rat Spinal Substantia Gelatinosa by Stereoisomers of Plant-Derived Chemicals

Activation of TRPV1, TRPA1 or TRPM8 channel expressed in the central terminal of dorsal root ganglion (DRG) neuron increases the spontaneous release of l-glutamate onto spinal dorsal horn lamina II (substantia gelatinosa; SG) neurons which play a pivotal role in regulating nociceptive transmission....

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Vydáno v:Pharmaceuticals (Basel)
Hlavní autoři: Kumamoto, Eiichi, Fujita, Tsugumi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039499/
https://ncbi.nlm.nih.gov/pubmed/27483289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph9030046
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