Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery

Demyelination in MS disrupts nerve signals and contributes to axon degeneration. While remyelination promises to restore lost function, it remains unclear whether remyelination will prevent axonal loss. Inflammatory demyelination is accompanied by significant neuronal loss in the experimental autoim...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Mei, Feng, Lehmann-Horn, Klaus, Shen, Yun-An A, Rankin, Kelsey A, Stebbins, Karin J, Lorrain, Daniel S, Pekarek, Kara, A Sagan, Sharon, Xiao, Lan, Teuscher, Cory, von Büdingen, H-Christian, Wess, Jürgen, Lawrence, J Josh, Green, Ari J, Fancy, Stephen PJ, Zamvil, Scott S, Chan, Jonah R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2016
Gaiak:
Neuroscience
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039026/
https://ncbi.nlm.nih.gov/pubmed/27671734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18246
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