Fluorescence in situ hybridization testing of chromosomes 6, 8, 9 and 11 in melanocytic tumors is difficult to automate and reveals tumor heterogeneity in melanomas

Malignant melanomas may be difficult to differentiate from benign nevi on the basis of histology. Contrary to nevi, the majority of melanomas harbor chromosomal imbalances. Comparative genomic hybridization-based and fluorescence in situ hybridization (FISH) tests can help differentiating malignant...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Uguen, Arnaud, Uguen, Marie, Talagas, Matthieu, Gobin, Eric, Marcorelles, Pascale, De Braekeleer, Marc
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2016
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038458/
https://ncbi.nlm.nih.gov/pubmed/27698849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4949
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