Fluorescence in situ hybridization testing of chromosomes 6, 8, 9 and 11 in melanocytic tumors is difficult to automate and reveals tumor heterogeneity in melanomas

Malignant melanomas may be difficult to differentiate from benign nevi on the basis of histology. Contrary to nevi, the majority of melanomas harbor chromosomal imbalances. Comparative genomic hybridization-based and fluorescence in situ hybridization (FISH) tests can help differentiating malignant...

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Publicado en:Oncol Lett
Main Authors: Uguen, Arnaud, Uguen, Marie, Talagas, Matthieu, Gobin, Eric, Marcorelles, Pascale, De Braekeleer, Marc
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2016
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038458/
https://ncbi.nlm.nih.gov/pubmed/27698849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4949
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