Population Pharmacokinetic Modeling of Tribendimidine Metabolites in Opisthorchis viverrini-Infected Adults

There is a pressing need for alternative treatments against the liver fluke Opisthorchis viverrini. Oral tribendimidine is a promising candidate, but its population pharmacokinetic properties are unknown. Two phase IIa trials were conducted in Laos in O. viverrini-infected adults receiving single or...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Vanobberghen, Fiona, Penny, Melissa A., Duthaler, Urs, Odermatt, Peter, Sayasone, Somphou, Keiser, Jennifer, Tarning, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038332/
https://ncbi.nlm.nih.gov/pubmed/27431233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00655-16
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