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Single-Ascending-Dose Pharmacokinetic Study of Tribendimidine in Opisthorchis viverrini-Infected Patients

Praziquantel is the only drug available for the treatment of Opisthorchis viverrini infections. Tribendimidine has emerged as a potential treatment alternative; however, its pharmacokinetic (PK) properties have not been sufficiently studied to date. Via two phase IIa dose-finding studies, 68 O. vive...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Duthaler, Urs, Sayasone, Somphou, Vanobbergen, Fiona, Penny, Melissa A., Odermatt, Peter, Huwyler, Jörg, Keiser, Jennifer
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038241/
https://ncbi.nlm.nih.gov/pubmed/27431234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00992-16
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