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Pharmacokinetic and Pharmacodynamic Evaluation of a Weight-Based Dosing Regimen of Cefoxitin for Perioperative Surgical Prophylaxis in Obese and Morbidly Obese Patients

The objective of this study was to determine the pharmacokinetics and pharmacodynamics (PK/PD) of a weight-based cefoxitin dosing regimen for surgical prophylaxis in obese patients. Patients received a single dose of cefoxitin at 40 mg/kg based on total body weight. Cefoxitin samples were obtained o...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Moine, Pierre, Mueller, Scott W., Schoen, Jonathan A., Rothchild, Kevin B., Fish, Douglas N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038324/
https://ncbi.nlm.nih.gov/pubmed/27458209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00585-16
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