Comparative Population Plasma and Tissue Pharmacokinetics of Micafungin in Critically Ill Patients with Severe Burn Injuries and Patients with Complicated Intra-Abdominal Infection

Severely burned patients have altered drug pharmacokinetics (PKs), but it is unclear how different they are from those in other critically ill patient groups. The aim of the present study was to compare the population pharmacokinetics of micafungin in the plasma and burn eschar of severely burned pa...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: García-de-Lorenzo, A., Luque, S., Grau, S., Agrifoglio, A., Cachafeiro, L., Herrero, E., Asensio, M. J., Sánchez, S. M., Roberts, J. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Clinical Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038299/
https://ncbi.nlm.nih.gov/pubmed/27458229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00727-16
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