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Comparative Population Plasma and Tissue Pharmacokinetics of Micafungin in Critically Ill Patients with Severe Burn Injuries and Patients with Complicated Intra-Abdominal Infection

Severely burned patients have altered drug pharmacokinetics (PKs), but it is unclear how different they are from those in other critically ill patient groups. The aim of the present study was to compare the population pharmacokinetics of micafungin in the plasma and burn eschar of severely burned pa...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: García-de-Lorenzo, A., Luque, S., Grau, S., Agrifoglio, A., Cachafeiro, L., Herrero, E., Asensio, M. J., Sánchez, S. M., Roberts, J. A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038299/
https://ncbi.nlm.nih.gov/pubmed/27458229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00727-16
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