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Glutamate Racemase Is the Primary Target of β-Chloro-d-Alanine in Mycobacterium tuberculosis

The increasing global prevalence of drug resistance among many leading human pathogens necessitates both the development of antibiotics with novel mechanisms of action and a better understanding of the physiological activities of preexisting clinically effective drugs. Inhibition of peptidoglycan (P...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Prosser, Gareth A., Rodenburg, Anne, Khoury, Hania, de Chiara, Cesira, Howell, Steve, Snijders, Ambrosius P., de Carvalho, Luiz Pedro S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038272/
https://ncbi.nlm.nih.gov/pubmed/27480853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01249-16
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