Fosfomycin Enhances the Activity of Daptomycin against Vancomycin-Resistant Enterococci in an In Vitro Pharmacokinetic-Pharmacodynamic Model

Daptomycin (DAP) is being used more frequently to treat infections caused by vancomycin-resistant enterococcus (VRE). DAP tends to be less active against enterococci than staphylococci and may require high doses or combination therapy to be bactericidal. Fosfomycin (FOF) has activity against VRE and...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Hall Snyder, Ashley D., Werth, Brian J., Nonejuie, Poochit, McRoberts, John P., Pogliano, Joe, Sakoulas, George, Yim, Juwon, Singh, Nivedita, Rybak, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038233/
https://ncbi.nlm.nih.gov/pubmed/27431211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00687-16
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