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Bone morphogenetic protein-2 provokes interleukin-18-induced human intervertebral disc degeneration
OBJECTIVES: Interleukin 18 (IL-18) is a regulatory cytokine that degrades the disc matrix. Bone morphogenetic protein-2 (BMP-2) stimulates synthesis of the disc extracellular matrix. However, the combined effects of BMP-2 and IL-18 on human intervertebral disc degeneration have not previously been r...
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Publicado no: | Bone Joint Res |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5037967/ https://ncbi.nlm.nih.gov/pubmed/27669712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1302/2046-3758.59.BJR-2016-0032.R1 |
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