Anthocyanin Attenuates Doxorubicin-Induced Cardiomyotoxicity via Estrogen Receptor-α/β and Stabilizes HSF1 to Inhibit the IGF-IIR Apoptotic Pathway

Doxorubicin (Dox) is extensively used for chemotherapy in different types of cancer, but its use is limited to because of its cardiotoxicity. Our previous studies found that doxorubicin-induced insulin-like growth factor II receptor (IGF-IIR) accumulation causes cardiomyocytes apoptosis via down-reg...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Huang, Pei-Chen, Kuo, Wei-Wen, Shen, Chia-Yao, Chen, Yu-Feng, Lin, Yueh-Min, Ho, Tsung-Jung, Padma, V. Vijaya, Lo, Jeng-Fan, Huang, Chih-Yang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037853/
https://ncbi.nlm.nih.gov/pubmed/27657062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17091588
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