p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure

Hypertension-induced cardiac hypertrophy and attenuated cardiac function are the major characteristics of early stage heart failure. Cardiomyocyte death in pathological cardiac conditions is the primary cause of heart failure and mortality. Our previous studies found that heat shock factor 1 (HSF1)...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Huang, Chih-Yang, Pai, Pei-Ying, Kuo, Chia-Hua, Ho, Tsung-Jung, Lin, Jing-Ying, Lin, Ding-Yu, Tsai, Fu-Jen, Padma, V Vijaya, Kuo, Wei-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596536/
https://ncbi.nlm.nih.gov/pubmed/28796250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.320
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