Pharmacogenetics Biomarkers and Their Specific Role in Neoadjuvant Chemoradiotherapy Treatments: An Exploratory Study on Rectal Cancer Patients

Background: Pathological complete response (pCR) to neoadjuvant chemoradiotherapy (CRT) in locally advanced rectal cancer (LARC) is still ascribed to a minority of patients. A pathway based-approach could highlight the predictive role of germline single nucleotide polymorphisms (SNPs). The primary a...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Dreussi, Eva, Cecchin, Erika, Polesel, Jerry, Canzonieri, Vincenzo, Agostini, Marco, Boso, Caterina, Belluco, Claudio, Buonadonna, Angela, Lonardi, Sara, Bergamo, Francesca, Gagno, Sara, De Mattia, Elena, Pucciarelli, Salvatore, De Paoli, Antonino, Toffoli, Giuseppe
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037760/
https://ncbi.nlm.nih.gov/pubmed/27608007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17091482
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