Pharmacogenetics Biomarkers and Their Specific Role in Neoadjuvant Chemoradiotherapy Treatments: An Exploratory Study on Rectal Cancer Patients

Background: Pathological complete response (pCR) to neoadjuvant chemoradiotherapy (CRT) in locally advanced rectal cancer (LARC) is still ascribed to a minority of patients. A pathway based-approach could highlight the predictive role of germline single nucleotide polymorphisms (SNPs). The primary a...

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Main Authors: Eva Dreussi, Erika Cecchin, Jerry Polesel, Vincenzo Canzonieri, Marco Agostini, Caterina Boso, Claudio Belluco, Angela Buonadonna, Sara Lonardi, Francesca Bergamo, Sara Gagno, Elena De Mattia, Salvatore Pucciarelli, Antonino De Paoli, Giuseppe Toffoli
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2016-09-01
Colecção:International Journal of Molecular Sciences
Assuntos:
pharmacogenetics
locally advanced rectal cancer
chemoradiotherapy
Acesso em linha:http://www.mdpi.com/1422-0067/17/9/1482
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