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Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis

Cholecystokinin (CCK) modulates contractility of the gallbladder, the sphincter of Oddi, and the stomach. These effects are mediated through activation of gastrointestinal smooth muscle as well as enteric neuron CCK-1 receptors (CCK-1Rs). To investigate the potential physiological and pathophysiolog...

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Wang, David Q.-H., Schmitz, Frank, Kopin, Alan S., Carey, Martin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2004
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC503765/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15314689/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16801
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