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Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis

Cholecystokinin (CCK) modulates contractility of the gallbladder, the sphincter of Oddi, and the stomach. These effects are mediated through activation of gastrointestinal smooth muscle as well as enteric neuron CCK-1 receptors (CCK-1Rs). To investigate the potential physiological and pathophysiolog...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Wang, David Q.-H., Schmitz, Frank, Kopin, Alan S., Carey, Martin C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC503765/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15314689/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16801
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