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High- and low-affinity binding of GRO alpha and neutrophil-activating peptide 2 to interleukin 8 receptors on human neutrophils.

GRO alpha and neutrophil-activating peptide 2 (NAP-2), like their analog interleukin 8 (IL-8), are considered to be inflammatory mediators since they recruit and activate neutrophil leukocytes. After introduction of tyrosines by substitution for other residues at the C terminus, GRO alpha and NAP-2...

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Bibliographic Details
Main Authors: Schumacher, C, Clark-Lewis, I, Baggiolini, M, Moser, B
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC50375/
https://ncbi.nlm.nih.gov/pubmed/1438244
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