Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8.

The interaction of interleukin 8 (IL-8) with heparin was studied by using synthetic IL-8 analogs with C- and N-terminal truncations. Elimination of the N-terminal region preceding the first cysteine, which constitutes the IL-8 receptor binding site, did not affect the affinity to heparin-Sepharose....

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Webb, L M, Ehrengruber, M U, Clark-Lewis, I, Baggiolini, M, Rot, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8346230/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.15.7158
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