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Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8.

The interaction of interleukin 8 (IL-8) with heparin was studied by using synthetic IL-8 analogs with C- and N-terminal truncations. Elimination of the N-terminal region preceding the first cysteine, which constitutes the IL-8 receptor binding site, did not affect the affinity to heparin-Sepharose....

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Detalhes bibliográficos
Main Authors: Webb, L M, Ehrengruber, M U, Clark-Lewis, I, Baggiolini, M, Rot, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47095/
https://ncbi.nlm.nih.gov/pubmed/8346230
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