The receptor for interleukin 3 is selectively induced in human endothelial cells by tumor necrosis factor alpha and potentiates interleukin 8 secretion and neutrophil transmigration.

Interleukin (IL)-3 stimulates hemopoiesis in vitro. However, IL-3 is not normally found in bone marrow, raising doubts as to the in vivo role of IL-3. We have found that human umbilical vein endothelial cells (HUVEC) express functional high-affinity receptors for IL-3 after stimulation with tumor ne...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Korpelainen, E I, Gamble, J R, Smith, W B, Goodall, G J, Qiyu, S, Woodcock, J M, Dottore, M, Vadas, M A, Lopez, A F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47937/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11137
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