The receptor for interleukin 3 is selectively induced in human endothelial cells by tumor necrosis factor alpha and potentiates interleukin 8 secretion and neutrophil transmigration.

Interleukin (IL)-3 stimulates hemopoiesis in vitro. However, IL-3 is not normally found in bone marrow, raising doubts as to the in vivo role of IL-3. We have found that human umbilical vein endothelial cells (HUVEC) express functional high-affinity receptors for IL-3 after stimulation with tumor ne...

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Main Authors: Korpelainen, E I, Gamble, J R, Smith, W B, Goodall, G J, Qiyu, S, Woodcock, J M, Dottore, M, Vadas, M A, Lopez, A F
格式: Artigo
語言:Inglês
出版: 1993
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC47937/
https://ncbi.nlm.nih.gov/pubmed/7504295
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