Immune Repertoire Diversity Correlated with Mortality in Avian Influenza A (H7N9) Virus Infected Patients

Specific changes in immune repertoires at genetic level responding to the lethal H7N9 virus are still poorly understood. We performed deep sequencing on the T and B cells from patients recently infected with H7N9 to explore the correlation between clinical outcomes and immune repertoire alterations....

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Pubblicato in:Sci Rep
Autori principali: Hou, Dongni, Ying, Tianlei, Wang, Lili, Chen, Cuicui, Lu, Shuihua, Wang, Qin, Seeley, Eric, Xu, Jianqing, Xi, Xiuhong, Li, Tao, Liu, Jie, Tang, Xinjun, Zhang, Zhiyong, Zhou, Jian, Bai, Chunxue, Wang, Chunlin, Byrne-Steele, Miranda, Qu, Jieming, Han, Jian, Song, Yuanlin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037391/
https://ncbi.nlm.nih.gov/pubmed/27669665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33843
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