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Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage

Guanylin (GN) and uroguanylin (UGN), through activation of guanylyl cyclase C (GCC), serve to control intestinal fluid homeostasis. Both peptides are produced in the intestinal epithelium, but their cellular origin has not been fully charted. Using quantitative PCR and an improved in situ hybridizat...

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Publicat a:Histochem Cell Biol
Autors principals: Ikpa, Pauline T., Sleddens, Hein F. B. M., Steinbrecher, Kris A., Peppelenbosch, Maikel P., de Jonge, Hugo R., Smits, Ron, Bijvelds, Marcel J. C.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037145/
https://ncbi.nlm.nih.gov/pubmed/27246004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00418-016-1453-4
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