Release of cathepsin-B in cytosol causes cell death in acute pancreatitis

BACKGROUND & AIMS: Experimental studies in acute pancreatitis (AP) suggest strong association of acinar cell injury with cathepsin-B dependent intracellular activation of trypsin. However, the molecular events subsequent to trypsin activation and their role, if any, in cell death have not been s...

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Publicado en:Gastroenterology
Main Authors: Talukdar, Rupjyoti, Sareen, Archana, Zhu, Hongyan, Yuan, Zuobiao, Dixit, Ajay, Cheema, Hassam, George, John, Barlass, Usman, Sah, Raghuwansh, Garg, Sushil K, Banerjee, Sulagna, Garg, Pramod, Dudeja, Vikas, Dawra, Rajinder, Saluja, Ashok K
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037034/
https://ncbi.nlm.nih.gov/pubmed/27519471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.06.042
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