Intratumoral interferon-gamma increases chemokine production but fails to increase T cell infiltration of human melanoma metastases

INTRODUCTION: Optimal approaches to induce T cell infiltration of tumors are not known. Chemokines CXCL9, CXCL10, and CXCL11 support effector T cell recruitment and may be induced by IFN. This study tests the hypothesis that intratumoral administration of IFNγ will induce CXCL9–11 and will induce T...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancer Immunol Immunother
Asıl Yazarlar: Mauldin, Ileana S., Wages, Nolan A., Stowman, Anne M., Wang, Ena, Smolkin, Mark E., Olson, Walter C., Deacon, Donna H., Smith, Kelly T., Galeassi, Nadedja V., Chianese‐Bullock, Kimberly A., Dengel, Lynn T., Marincola, Francesco M., Petroni, Gina R., Mullins, David W., Slingluff, Craig L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2016
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037033/
https://ncbi.nlm.nih.gov/pubmed/27522581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1881-y
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller