TetraMabs: simultaneous targeting of four oncogenic receptor tyrosine kinases for tumor growth inhibition in heterogeneous tumor cell populations

Monoclonal antibody-based targeted tumor therapy has greatly improved treatment options for patients. Antibodies against oncogenic receptor tyrosine kinases (RTKs), especially the ErbB receptor family, are prominent examples. However, long-term efficacy of such antibodies is limited by resistance me...

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Detalhes bibliográficos
Publicado no:Protein Eng Des Sel
Main Authors: Castoldi, Raffaella, Schanzer, Jürgen, Panke, Christian, Jucknischke, Ute, Neubert, Natalie J., Croasdale, Rebecca, Scheuer, Werner, Auer, Johannes, Klein, Christian, Niederfellner, Gerhard, Kobold, Sebastian, Sustmann, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036864/
https://ncbi.nlm.nih.gov/pubmed/27578890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzw037
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