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The Composition of Rosenthal Fibers, the Protein Aggregate Hallmark of Alexander Disease
Alexander disease (AxD) is a neurodegenerative disorder characterized by astrocytic protein aggregates called Rosenthal fibers (RFs). We used mouse models of AxD to determine the protein composition of RFs to obtain information about disease mechanisms, including the hypothesis that sequestration of...
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| Publicado en: | J Proteome Res |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5036859/ https://ncbi.nlm.nih.gov/pubmed/27193225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00316 |
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