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The role of charged surface residues in the binding ability of small hubs in protein-protein interaction networks

Hubs are highly connected proteins in a protein-protein interaction network. Previous work has implicated disordered domains and high surface charge as the properties significant in the ability of hubs to bind multiple proteins. While conformational flexibility of disordered domains plays an importa...

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Библиографические подробности
Опубликовано в: :Biophysics (Nagoya-shi)
Главные авторы: Patil, Ashwini, Nakamura, Haruki
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society of Japan (BSJ) 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036656/
https://ncbi.nlm.nih.gov/pubmed/27857564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysics.3.27
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